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M9490402.TXT
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1994-09-19
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Document 0402
DOCN M9490402
TI A human immunodeficiency virus type 1 (HIV-1)-based retroviral vector
system utilizing stable HIV-1 packaging cell lines.
DT 9411
AU Carroll R; Lin JT; Dacquel EJ; Mosca JD; Burke DS; St Louis DC; Research
Laboratory, Henry M. Jackson Foundation for the; Advancement of Military
Medicine, Rockville, Maryland.
SO J Virol. 1994 Sep;68(9):6047-51. Unique Identifier : AIDSLINE
MED/94335122
AB We have constructed stable human immunodeficiency virus (HIV) packaging
cell lines that when transfected with an HIV-based retroviral vector
produce packaged vectors capable of transducing susceptible CD4+ cells.
This HIV-1-based retroviral vector system has the potential for
providing targeted delivery and regulated expression of immunogens or
antiviral agents in CD4+ cells.
DE Animal Cell Line Cercopithecus aethiops *Genetic Vectors
HIV-1/*GENETICS In Vitro Transduction, Genetic Virus Replication
JOURNAL ARTICLE
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).